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Melissa Wright

Melissa Wright

Pediatric autoimmune neurologist and Director of the Pediatric Autoimmune Neurology and Neuroimmunology Program at Primary Children's Hospital, University of Utah.

Jun 30, 2026

16:38
Looking at the future, if we were having this conversation 10 years from now, what advances would you hope to see in how we diagnose, treat and study autoimmune encephalitis in children?
16:49
Oh, I love this question so much in it because there's so many things I hope to see.
16:52
And this is probably a question I could spend the rest of the time talking about in terms of different ways that I see the field going.
17:01
It's interesting that you ask this because when I'm in the hospital and I'm teaching trainees and discussing the field of autoimmune neurology or discussing a specific treatment approach, with them, I often tell them that I likely, the way that I'm treating patients now likely won't be the same as I'm treating them in 10, 15, 20 years.
17:22
And that, you know, is not meant to be like a heavy, like discouraging thought, but more of an exciting and hopeful one that I discuss with them that I know that, you know, we're doing the best with what evidence we have, but I'm very hopeful that in the And so, you know, I think we're entering a very exciting phase in autoimmune encephalitis of this sort of prospective, an era of prospective treatment trials.
17:51
We no longer are going to be needing to just always rely on those retrospective studies, but we were seeing this forward motion of prospective trials.
18:01
And, you know, and once we start getting data from those trials, it's going to be really exciting to see how it takes the field and what information that we get from it.
23:09
And I was just wondering if you could tell us about your experience in enrolling pediatric patients for the extinguish trial that you're working on.
43:21
were you concerned when you heard that the EU had decided to ban it? No.
43:25
For me personally, we have already had a product that we manufacture ourselves in the EU and we already had that on the market without TPO or hemerin anyway.
43:39
So for us, it wasn't particularly worrying, but it was worrying for the industry as a whole because it kind of shone light on, you know, how...
43:48
People could be scared of having their nails done or people could be worried about having, you know, build a gel for the foreseeable and not be educated and know that that particular product, it is going to cause a little bit of a stir.
44:01
But it's putting the power into the client's hands, which I quite like to know that they can choose where to go.
44:09
To feel safe.

8 MINS LATER

52:06
Watch out for that chemical.
52:08
No, I don't think anyone would like to stop getting their nails done.

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