
Melissa Wright
Pediatric autoimmune neurologist and Director of the Pediatric Autoimmune Neurology and Neuroimmunology Program at Primary Children's Hospital, University of Utah.
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Jun 30, 2026
Ep 73 - Paediatric Autoimmune Encephalitis with Dr Melissa Wright
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Prav PrathapanHOST
Looking at the future, if we were having this conversation 10 years from now, what advances would you hope to see in how we diagnose, treat and study autoimmune encephalitis in children?

Melissa WrightGUEST
Oh, I love this question so much in it because there's so many things I hope to see.

Melissa WrightGUEST
And this is probably a question I could spend the rest of the time talking about in terms of different ways that I see the field going.

Melissa WrightGUEST
It's interesting that you ask this because when I'm in the hospital and I'm teaching trainees and discussing the field of autoimmune neurology or discussing a specific treatment approach, with them, I often tell them that I likely, the way that I'm treating patients now likely won't be the same as I'm treating them in 10, 15, 20 years.

Melissa WrightGUEST
And that, you know, is not meant to be like a heavy, like discouraging thought, but more of an exciting and hopeful one that I discuss with them that I know that, you know, we're doing the best with what evidence we have, but I'm very hopeful that in the And so, you know, I think we're entering a very exciting phase in autoimmune encephalitis of this sort of prospective, an era of prospective treatment trials.

Melissa WrightGUEST
We no longer are going to be needing to just always rely on those retrospective studies, but we were seeing this forward motion of prospective trials.

Melissa WrightGUEST
And, you know, and once we start getting data from those trials, it's going to be really exciting to see how it takes the field and what information that we get from it.

Prav PrathapanHOST
And I was just wondering if you could tell us about your experience in enrolling pediatric patients for the extinguish trial that you're working on.
Brigitte Macron cyberbullying case, Comedian Laura Smyth, Autism de-diagnosis
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Melissa WrightGUEST
For me personally, we have already had a product that we manufacture ourselves in the EU and we already had that on the market without TPO or hemerin anyway.

Melissa WrightGUEST
So for us, it wasn't particularly worrying, but it was worrying for the industry as a whole because it kind of shone light on, you know, how...

Melissa WrightGUEST
People could be scared of having their nails done or people could be worried about having, you know, build a gel for the foreseeable and not be educated and know that that particular product, it is going to cause a little bit of a stir.

Melissa WrightGUEST
But it's putting the power into the client's hands, which I quite like to know that they can choose where to go.
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