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Melissa Cooper

Jul 30, 2026

23:00
... and how strong a signal is.
23:02
So I felt it was really important for me to actually see the entire system as a whole.
23:08
So here is another way that I'm manipulating on the sample side, which is, like, an important part of microscopy, just like with expansion microscopy.
23:16
It's always important to think about both your scope and your sample.
23:19
So here, I take the lipids out of my sample and then match the refractive index of protein to the solution that I have it in, and that makes it such that the proteins, which are all that's left in the brain, match the actual solution, which actually matches glass.
23:38
So then to the microscope, everything looks clear, and that means that I can just see what's glowing, which are the things that I've tagged.

34 MINS LATER

58:03
Mm.

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