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Mel Chan

Mel Chan

Nephrologist and IPPRF Research Fellow at Imperial College London specializing in genetic kidney disease.

Jul 21, 2026

7:59
Go on, give us the potted summary of ADPKD,
8:02
polycystic kidney disease.
8:05
So AUPKD is common.
8:07
It affects around one in a thousand people, as I mentioned earlier.
8:11
And this is a condition where we get multiple fluid-filled cysts that grow in the kidneys and sometimes the liver, which over time cause the kidneys to enlarge and then gradually lose function.
8:22
This is usually inherited from a parent and is an autosomal dominant condition.
8:26
So it's passed on to 50% of all children, regardless of the sex.

7 MINS LATER

15:29
But women can get this too, can't they? Even though it's X-linked, it's not just in boys, isn't that right?

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