When it came to sort of setting up the study then, how did you control for calories in the three different diets

as variables? Right.

So what we wanted to do was take people who had obesity and metabolic disease who would stand to gain from weight loss, who would stand to benefit metabolically from losing weight.

So they had to have prediabetes and fatty liver or hepatic steatosis to get into the study along with obesity.

And then we wanted to control the variable of weight loss.

We wanted everybody to lose approximately 10% of body weight so that we could isolate differences among the diets at the same level of body weight reduction.

And so the way we did that was to provide participants with all of their food as a certain number of 500 calorie entrees and snacks that were picked up by the participants weekly from our metabolic kitchen and consumed.

Do you think the keto group in your study could have preferential longevity benefits from this intervention in a way that the other two groups might not access?