Um, can you relate those two for me and just tell me what are they actually doing physiologically for us? And that'll form the foundation of where GLP-1As fit in, I guess.

Yeah, of course.

Um, we can start with ghrelin.

That's reasonably simple.

Ghrelin is probably or arguably one of the most important, um, hunger signaling, um, hormones that we have.

It's produced predominantly in our stomachs as a response to them being empty, and it makes us feel hungry.

Um, the incretins endogenously, they, in, in our bodies under natural physiology, they have the opposite effect.

... um, that lasts longer, yeah?