
Mary Wojnaroski
Clinical psychologist at Nationwide Children's Hospital and Assistant Professor of Pediatrics at Ohio State, specializing in neurodevelopmental disabilities and co-investigator on the Inchstone Project.
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OCT 5
Sep 20, 2026
Clinical Trials – what you need to know about outcome measures
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Alicia HalladayHOST
So can you describe what sorts of challenges those people have and why it's important to monitor progress in that group? Why it's especially important to monitor progress?

Mary WojnaroskiGUEST
So developmental and epileptic encephalopathy, we use that term for individuals who have functional impairments or difficulties that are driven both by an underlying cause, like a genetic disorder or some sort of structural brain difference, and also have intractable epilepsy or seizures that are impacting their functional ability.

Mary WojnaroskiGUEST
So that's the term that we use to describe Those group, that group of individuals, they are often impacted by a lot of different things.

Mary WojnaroskiGUEST
So they don't just have developmental delays and seizures, but maybe also motor difficulties or respiratory involvement, feeding issues, sleeping issues.

Mary WojnaroskiGUEST
So it's really... a disorder that impacts lots and lots of different body systems and areas of functioning.
21 MINS LATER