M
Madeline King
1
APPEARANCES
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May 11, 2026
BONUS: Mailbag - Should patients stop antibiotics early if they feel better?
S
2:02Steve SmallHOST
Yeah, that's a great point, and I'm kinda curious, where then are all these durations we hear about coming from? Like, how [chuckles] are, are we just throwing darts at a dartboard and seeing what sticks? Where are these-- Where, where do we get these ideas on durations?
M
2:19Madeline KingGUEST
Um, and if you go back to an article from, uh, Dr. Paul Sax from, like, 2010, kind of a parody article, he talks about how we get five days from the number of fingers you have on one hand and seven days from the number of days in one week.
M
2:38Madeline KingGUEST
Um, and it may be where we started back when antibiotics were first being used, um, 80 years ago.
M
2:45Madeline KingGUEST
However, we do have a lot of actual evidence and literature over the past few decades, um, that compares short to long courses of antibiotics.
M
2:54Madeline KingGUEST
Um, and so we've used that literature to kind of base our guidelines on how to treat these infections, showing, you know, if five versus seven days you have no difference in outcomes, then we're gonna recommend five days in our guidelines.