
Logan Thrasher Collins
PhD candidate in biomedical engineering at Washington University in St. Louis; co-founder of Cathedral Therapeutics (acquired by General Cybernetics, 2025); expert in gene therapy delivery systems and synthetic biology.
1
APPEARANCES
1
PODCASTS
012
DEC 30
JAN 6
JAN 13
JAN 20
JAN 27
FEB 3
FEB 10
FEB 17
FEB 24
MAR 3
MAR 10
MAR 17
MAR 24
MAR 31
APR 7
APR 14
APR 21
APR 28
MAY 5
MAY 12
MAY 19
MAY 26
JUN 2
JUN 9
JUN 16
JUN 23
JUN 30
JUL 7
JUL 14
JUL 21
JUL 28
AUG 4
AUG 11
AUG 18
AUG 25
SEP 1
SEP 8
SEP 15
SEP 22
SEP 29
OCT 6
OCT 13
OCT 20
OCT 27
NOV 3
NOV 10
NOV 17
NOV 24
DEC 1
DEC 8
DEC 15
DEC 22
DEC 29
JAN 5
JAN 12
JAN 19
JAN 26
FEB 2
FEB 9
FEB 16
FEB 23
MAR 2
MAR 9
MAR 16
MAR 23
MAR 30
APR 6
APR 13
APR 20
APR 27
MAY 4
MAY 11
MAY 18
MAY 25
JUN 1
JUN 8
JUN 15
JUN 22
JUN 29
JUL 6
JUL 13
JUL 20
JUL 27
AUG 3
AUG 10
AUG 17
AUG 24
AUG 31
SEP 7
SEP 14
SEP 21
Jul 5, 2026
Logan Thrasher Collins: The Trojan Horse That Could Fix Gene Therapy | Frameshifts Episode #14
15:28
21:17

Benjamin AryaHOST
Uh, talk, talk to us a little bit about, you know, what are protein vaults? And then we can go back and just, you know, talk about the ancestry of the entire delivery space as well.
15:39
So I, I should say that I, I'm the inventor of, uh, specifically protein vaults for delivery of viruses, um, and just to sort of clarify that first.
15:50
But as to what protein vaults are, um, so protein vaults are a mysterious organelle.
15:57
They're composed of 78 copy of a protein called major vault protein.
16:00
They look like, uh, two cups stuck together that have sort of a specific structure, and these cups, uh, are kind of...
5 MINS LATER

Benjamin AryaHOST
Um, talk to us about what was the v- like the first delivery, uh, mechanism that you were aware of and, and, uh, what was the-- Yeah, how, how did the field sort of progress since then?
