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Lindsey Westerhof

Ambulatory care clinical pharmacist (PharmD, BCACP) at Trinity Health Michigan in Grand Rapids, MI, and iForumRx.org podcast guest.

Oct 2, 2026

2:56
Can you explain the biological mechanism by which this happens, and how does breathing in tiny particles raise our blood pressure? And what do we already know about the, the benefits of HEPA filters in terms of their impact on blood pressure?
3:14
So without a doubt, particulate matter from air pollution does create a negative impact on health.
3:20
So for a brief background, particulate matter is a mix of solid and liquid droplets suspended in the air, defined as coarse or fine based on the size.
3:30
The fine particle size being two point five micrometers or less is small enough to penetrate our lungs and enter the bloodstream.
3:39
This can trigger oxidative stress and inflammation that leads to elevations in blood pressure and heart rate, and it's also been shown to worsen conditions like asthma and COPD.
3:50
This fine particulate matter can also come from other sources aside from air pollution from highways, indoor sources, so things like mold spores, dust mites, tobacco smoke, cooking and burning wood, candles or incense.
4:06
The kind of people that are at greatest risk of experiencing complications from this are probably people that have existing heart or lung diseases, children and older adults, and those with lower socioeconomic status.

6 MINS LATER

10:50
How generalizable are the results? And, and when a patient walks in and says they read something about using an air purifier and how it might lower their blood pressure, what should we tell them?

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