L
Lindsey Westerhof
Ambulatory care clinical pharmacist (PharmD, BCACP) at Trinity Health Michigan in Grand Rapids, MI, and iForumRx.org podcast guest.
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Oct 2, 2026
Relieve the Pressure! Can HEPA Filters Reduce Blood Pressure for Individuals Living in Environments with High Air Pollution?
2:56
10:50

Stuart HaynesHOST
Can you explain the biological mechanism by which this happens, and how does breathing in tiny particles raise our blood pressure? And what do we already know about the, the benefits of HEPA filters in terms of their impact on blood pressure?
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3:14Lindsey WesterhofGUEST
So without a doubt, particulate matter from air pollution does create a negative impact on health.
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3:20Lindsey WesterhofGUEST
So for a brief background, particulate matter is a mix of solid and liquid droplets suspended in the air, defined as coarse or fine based on the size.
L
3:30Lindsey WesterhofGUEST
The fine particle size being two point five micrometers or less is small enough to penetrate our lungs and enter the bloodstream.
L
3:39Lindsey WesterhofGUEST
This can trigger oxidative stress and inflammation that leads to elevations in blood pressure and heart rate, and it's also been shown to worsen conditions like asthma and COPD.
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3:50Lindsey WesterhofGUEST
This fine particulate matter can also come from other sources aside from air pollution from highways, indoor sources, so things like mold spores, dust mites, tobacco smoke, cooking and burning wood, candles or incense.
L
4:06Lindsey WesterhofGUEST
The kind of people that are at greatest risk of experiencing complications from this are probably people that have existing heart or lung diseases, children and older adults, and those with lower socioeconomic status.
6 MINS LATER

Stuart HaynesHOST
How generalizable are the results? And, and when a patient walks in and says they read something about using an air purifier and how it might lower their blood pressure, what should we tell them?