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Lin Chang

Lin Chang

Researcher

Sep 30, 2026

18:28
And I know we're not going to dive deep into this, but generally speaking, what do you tell your patients? And again, this is probably a conversation with their provider.
18:38
Well, I do have a fair amount of patients which are on what we call a neuromodulator, or you call it a gut-brain neuromodulator.
18:46
So they can help mood, but they also help reduce anxiety.
18:50
diarrhea, which you're probably not going to have as much of a problem during pregnancy, but also helps reduce pain.
18:56
So there's different categories.
18:58
There's the tricyclic antidepressants that we use at low doses.
19:02
And then there's SSRIs, which are very commonly known.

10 MINS LATER

28:38
Can you walk us through a little bit about what to look out for if there's some worsening GI symptoms because of that? And how early does that show up?
1:36
what was it like practicing during that era and when did it take to help shift the paradigm toward a multifactorial model of altered gut brain communication involving neuroimmune microbial and gastrointestinal physiological dysregulation
1:51
i've been in the field for a long time back when i started Yeah, a lot of people didn't even know what IBS, even other conditions were, if they were real or even understood the term.
2:07
Now, currently, you know, everybody knows what IBS, probably more recognizable than irritable bowel syndrome.
2:13
They just may not understand what it is completely, but at least they recognize that it is a condition that is common and they usually know somebody that has it.
2:23
But before, it really just wasn't even recognized.
2:26
They didn't understand it.
2:27
We definitely didn't have as much science to support the term disorders with gut-brain interaction and the multifactorial relationship.

23 MINS LATER

25:41
Was it an emotional toll of a particular difficult case or an aha moment? Or how do you manage the toll of patients coming to you that are really troubled? And as I think Kate mentioned earlier, some are told that it's all in their head and they're not believed and they've been seeking support for so long.
Jeffrey RobertsMODERATOR
2:24
What was it like practicing during that era and when did it take to help shift the paradigm toward a multifactorial model of altered gut-brain communication involving neuroimmune, microbial, and gastrointestinal physiological dysregulation?
2:38
I've been in the field for a long time.
2:41
Back when I started, Yeah, a lot of people didn't even know what IBS, even other conditions were, if they were real or even understood the term.
2:53
And Now, currently, you know, everybody knows what IBS, probably more recognizable than irritable bowel syndrome.
3:00
They just may not understand what it is completely, but at least they recognize that it is a condition that is common and they usually know somebody that has it.
3:11
But before, it really just wasn't even recognized.
3:14
They didn't understand it.

23 MINS LATER

Jeffrey RobertsMODERATOR
26:29
Was it an emotional toll of a particular difficult case or an aha moment or Or how do you manage the toll of patients coming to you that are really troubled? And as I think Kate mentioned earlier, some are told that it's all in their head and they're not believed and they've been seeking support for so long.

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