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Leslie Kenney

Leslie Kenney

Founder and CEO of Oxford Healthspan, longevity expert specializing in healthy aging compounds and autoimmune disease remission.

Jul 21, 2026

5:58
Can you take us back to, number one, that moment? What was going on and, and was that, uh, like a major pivot, or was, was sickness or illness, not feeling well a part of your life up until that point?
6:10
point?Well, um, infertility was a big part of my life up until that point.
6:17
I'd been trying, um, with my husband to get pregnant for eight years then, and unsuccessfully, three IUIs, was on my fifth round of IVF.
6:28
I had gone from being 38 with idiopathic infertility, the fancy word for we have no idea what kind of infertility you have, to tipping into age 39 and having geriatric infertility, 'cause obviously it's your age.
6:43
And I was waiting for donor eggs, um, but they were all arranged, and, uh, I noticed some pain in my hands.
6:53
Uh, I was using scissors trying to cut some ornaments for the Christmas tree and found that it was really painful.
7:01
Turning faucets and turning doorknobs was excruciating.

32 MINS LATER

38:38
Yeah.
6:05
Mm-hmm.
6:06
And, uh, we can go into the nuts and bolts of this, but this is based on published scientific literature.
6:11
And so because of the fact that there is a lot of crosstalk between these hallmarks of aging, it's kind of like at home when you clean one room in your house, suddenly you feel better about everything else and the ability to clean the other rooms in the house.
6:29
Simply by improving autophagy itself, you will have a positive spillover effect on another hallmark.
6:35
Let's say that's mitochondrial dysfunction or maybe that's protein folding.
6:40
But this crosstalk is real.
6:42
And, you know, if I think about the most impactful things that I can do as an individual to slow the aging process, I want more bang for my buck, and I want to hit as many of those hallmarks as possible, and spermidine really does that.

9 MINS LATER

15:50
Mm-hmm.

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