Why is that?

Because ultraviolet exposure is a true disease trigger in lupus, not just a cosmetic aggravator.

UV radiation can induce keratinocyte injury and apoptosis, increase exposure of nuclear autoantigens, and amplify innate immune signaling, including the interferon axis that sits at the center of lupus immunopathology.

So in practical terms, UV exposure can trigger cutaneous flares and can sometimes contribute to broader disease activation.

So photoprotection is an essential treatment, not a lifestyle advice.

And as dermatologists and clinicians treating patients with cutaneous manifestations of lupus, emphasizing the importance of strict sun protection is critical.

So my practical sunscreen advice is broad-spectrum, high SPF every day, and not just when it feels sunny.

So what would you do?