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Lalana Songra
Dr Lalana Songra, Medical Advisor and Chair of the Medical & Scientific Advisory Board at Examen Lab, a male fertility diagnostics company.
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Sep 30, 2026
Sperm DNA Fragmentation: What You Need to Know
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19:23ShaunHOST
Do they need to immediately go for DNA fragmentations?
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19:25Lalana SongraGUEST
got you it's a really good question and I guess there's quite a lot of conversation on this topic as to whether it's something that should be routine and at the minute there's not a guideline that would say that every person who's coming into a fertility clinic should be tested especially in the early stages however it's one of those things that so semen analysis as you say is like has been around and has been the mainstay for male fertility assessment for decades and it is does provide really important information as you've spoken about you know whether there are sperm there that are present that's the first step to understand how they move what they look like but what it doesn't tell you is that how um the kind of genetic integrity of the sperm.
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20:16Lalana SongraGUEST
And so that is when you think about it, one of the most important things that you can understand, because it's only the DNA that is traveling kind of forward in the journey.
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20:25Lalana SongraGUEST
Once it's once it's passed fertilization, that's the only part of the sperm that's kind of making it through.
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20:33Lalana SongraGUEST
So if semen analysis isn't really telling you as much about that, then you've got potentially an incomplete assessment of sperm.
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20:42Lalana SongraGUEST
And so early on, you could consider that if you are trying for a baby and you're in that preconception period, perhaps you've been trying for three to six months.
17 MINS LATER
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38:22CiaranHOST
Yeah.