How do stage 1 and stage 2 present, Katie?

So Jess, in stage one, the hemolymphatic phase, symptoms are notoriously nonspecific, frequently misdiagnosed as malaria, typhoid, or flu.

Patients present with intermittent fever, malaise, headache.

joint pain, generalized pruritus, or rash.

A trypanosomal chancre, a painful, indurated nodule at the bite site, appears in about 50% of Rhodosciency cases but is less common in Gambiancy.

A pathognomonic sign in Gambiancy hat is Winterbottom's sign, painless enlarged rubbery lymph nodes in the posterior cervical triangle.

Katie, can you run us through some take-home points?

I sure can, Jess.