So I know that strength means heavy loads, right? But yeah, what's the minimum effective dose? How do we, do we want to maintain? Do we want to grow? Talk to us about strength.

Yeah, yeah.

Same relationship.

And there's a dose dependent sort of one here, meaning the more lifting that you do, provided it is heavy enough to make you get stronger and you can recover from it.

Well, you're going to get more strength gain.

And to my mind, because most people are not yet maximizing their health benefit from strength.

Most people should be aiming to get stronger.

There's a big component, but what can we do about bone mineral density?

Can you maybe explain actually what those discussions were, what they meant, and what they didn't mean?

Yeah.

So an FDA-approved medication in the United States basically means that the agent has gone through the appropriate clinical trials, and the FDA has said, "Yeah, we think that for these particular indications at these doses, this seems to have some sort of use case there.

We have a relatively well-characterized safety profile to the extent it can be known, relatively good efficacy profile, again, to the extent it can be known.

But by the way, we're gonna monitor this after it's been released onto the market, postmar- market surveillance." That's actually, like, a phase four clinical trial, right? It's just always ongoing.

And so it doesn't mean that all FDA-approved medications are 100% safe without risk.

It just means that we tend to know more about them.

But here's fingers crossed for more studies.

What arguments would you be bringing against you? And then how would you answer those?

Sure.

Yeah, it's a great question.

So the first argument would be like, well, look, the reason why there are no studies here is because now, since they're already out on the market, pharmaceutical companies, big pharma can't actually make their money back, even though they did develop these things and did some initial research.

And to that, I say...

It's going to be harder for them, for sure.

They will either have to create some sort of patented delivery system.

Apparently, bodegas in New York are selling peptides.

Is it like 38%?

38% was lean mass loss.

Now, there's some scientific literacy issues here, not just among the lay public, but cert- in the clinical community.

Lean mass, as you guys all know, is not just contractile muscle tissue.

That refers to anything that's not fat mass.

Yeah.

So, uh, that's thing one.

Mm-hmm

What, what, what is-- what are peptides?

Yeah.

I think, uh, this is actually a pretty interesting thing when you see it discussed online.

So peptides, uh, people will say, "Oh, they're just these short chains of amino acids," which is true from a pure chemistry standpoint.

But when you're talking about something that's not a food, not a dietary supplement, um, has a therapeutic intent, right? That means it's a medication.

Um, you could call it a drug, a medication, whatever.

It's n- neutral terms.

... basic understanding of science.

... keep those fibers.

And we see a, a big time slowing of that decline.

Like, we can't beat Father Time.

It, time is undefeated, right? But as far as the actual strength loss, it seems to be going down far slower in individuals who lift weights compared to those who, who don't.

Uh, so much so that, like, you might not notice a decline until somebody's in their 60s or 70s, and that decline is a relative decline.

They're like, "Well, I can't lift this much anymore, but I'm still functionally independent.

I can do everything I wanna do.

Mm-hmm.

So one, what is the mechanism? Uh, let's start with what is the mechanism?

Sure.

BPC-157's acronym's supposed to stand for body protective compound.

It was isolated from gastric juices, so stuff in your stomach, your stomach acid.

And the thought was, "Well, look, the stomach is this harsh environment, hostile environment, and those cells have to turn over on a regular basis, um, so you don't get an ulcer.

So maybe there's something in your stomach acid that's preve- that's either causing these cells to turn over or protecting these cells." Anyway, that's where they isolated BPC-157 from.

The thought is that it increases blood vessel growth, which we call angiogenesis, in particular at the level of the tendons or ligaments.

Mm-hmm.