John, I wonder if you could talk to this.

Yeah, absolutely.

Very happy to talk about this.

I've done a bit of work on HPV vaccine uptake and the costs of HPV-related cancer in our society.

So I do have some knowledge about the background of this.

And I think before I answer the question directly, a little bit of background is necessary.

There is a definite epidemiological shift in head and neck cancers, and many people may not be aware that While tobacco and alcohol-related oral cavity and laryngeal cancers have stabilized in numbers and in some regions even declined, there is a big increase in viral-related oropharyngeal squamous cell carcinoma, specifically tonsil cancer and base of tongue cancer.

So John, what was his diagnosis? What treatment did he receive?