So now we're going to move on and I am going to pass it to Dr. Cohen and he's going to take us through mechanisms that matter.

Thank you very much.

Thanks for setting the stage there.

I think we're ready now to talk a little bit about mechanisms.

And I think, you know, while we all kind of use these medications every day and treat our patients with these medications, it is important to understand the mechanism of action of the medications so that we know really what we're doing immunologically.

We're interfering in immune responses, and we should understand what we're doing so that we can pick the best medication.

So right now, we're going to talk about TIK2 inhibition in context, why selectivity and pathway targeting matter in clinical practice.

Yeah, because I've seen that before.