
Jay Hartenbach
1
APPEARANCES
1
PODCASTS
012
DEC 30
JAN 6
JAN 13
JAN 20
JAN 27
FEB 3
FEB 10
FEB 17
FEB 24
MAR 3
MAR 10
MAR 17
MAR 24
MAR 31
APR 7
APR 14
APR 21
APR 28
MAY 5
MAY 12
MAY 19
MAY 26
JUN 2
JUN 9
JUN 16
JUN 23
JUN 30
JUL 7
JUL 14
JUL 21
JUL 28
AUG 4
AUG 11
AUG 18
AUG 25
SEP 1
SEP 8
SEP 15
SEP 22
SEP 29
OCT 6
OCT 13
OCT 20
OCT 27
NOV 3
NOV 10
NOV 17
NOV 24
DEC 1
DEC 8
DEC 15
DEC 22
DEC 29
JAN 5
JAN 12
JAN 19
JAN 26
FEB 2
FEB 9
FEB 16
FEB 23
MAR 2
MAR 9
MAR 16
MAR 23
MAR 30
APR 6
APR 13
APR 20
APR 27
MAY 4
MAY 11
MAY 18
MAY 25
JUN 1
JUN 8
JUN 15
JUN 22
JUN 29
JUL 6
JUL 13
JUL 20
JUL 27
AUG 3
AUG 10
AUG 17
AUG 24
AUG 31
SEP 7
SEP 14
SEP 21
SEP 28
OCT 5
OCT 12
OCT 19
Jul 2, 2026
Exploring Dendritic Cell Therapy for Solid Tumors with Diakonos Oncology's Jay Hartenbach
4:18
4:23
4:36
4:40

Jay HartenbachGUEST
And so when we look at prior dendritic cell therapies, you really could put them into two different groups.

Jay HartenbachGUEST
There's a couple that, that tried some, uh, you know, really, uh, off the charts approaches, but most approaches were either taking the patient's tumor-derived lysate or mRNA and loading that into the dendritic cell.

Jay HartenbachGUEST
And when we think about dendritic cells, they're the master regulator of adaptive immunity.

Jay HartenbachGUEST
And so the thought behind dendritic cells was, if we can get dendritic cells to recognize the cancer as a threat, then we'll get the benefits of a complete top-down immune response.
11 MINS LATER
E
15:29Erin HarrisHOST
Um, so as Diakonos moves DOC ten twenty-one into a new Phase 1/2 trial in refractory melanoma and continues its Phase 2 GBM and Phase 1 pancreatic cancer programs like we were talking about, uh, what would you say are the most important scientific and operational milestones you and your team have focused on? Uh, and then how do you see these programs informing the next generation of dendritic cell-based immunotherapies?