Islam Mohamed
Radiation oncologist and Chief Medical Officer of Onco-Innovations Ltd. (CBOE CA: ONCO), previously a staff radiation oncologist at BC Cancer - Kelowna for over 25 years.
2
APPEARANCES
1
PODCASTS
Sep 10, 2026
Carmel FisherHOST
According to you and what you've seen so far, what is the single best piece of evidence that you have that this actually works?
Islam MohamedGUEST
Well, I would say probably the most important experiment comes out of the University of Alberta.
Islam MohamedGUEST
That's where all the foundational science supporting our drug candidate comes from.
Islam MohamedGUEST
It was published by Sadat and his colleagues at the University of Alberta in a 2021 paper published in the Journal of Controlled Release.
Islam MohamedGUEST
And what they had done is they took the nano-formulated PNKP inhibitor, that's the formulation that we tend to carry into humans, and they tested it in P10 deficient colorectal cancer xenografts.
Islam MohamedGUEST
So a xenograft is a human tumor grown in a mouse, and it is the standard means of establishing whether a compound does anything genuine to a human cancer before we test it in humans.
Islam MohamedGUEST
So in that experiment, the encapsulated drug demonstrated single agent antitumor activity.
6 MINS LATER
Carmel FisherHOST
Tell us more about that total addressable market and how do investors stand to make some return on their investment here?
Carmel FischerHOST
According to you and what you've seen so far, what is the single best piece of evidence that you have that this actually works?
Islam MohamedGUEST
Well, I would say probably the most important experiment comes out of the University of Alberta.
Islam MohamedGUEST
That's where all the foundational science supporting our drug candidate comes from.
Islam MohamedGUEST
It was published by Sadat and his colleagues at the University of Alberta in a 2021 paper published in the Journal of Controlled Release.
Islam MohamedGUEST
And what they had done is they took the nano-formulated PNKP inhibitor, that's the formulation that we tend to carry into humans, and they tested it in P10 deficient colorectal cancer xenografts.
Islam MohamedGUEST
So a xenograft is a human tumor grown in a mouse, and it is the standard means of establishing whether a compound does anything genuine to a human cancer before we test it in humans.
Islam MohamedGUEST
So in that experiment, the encapsulated drug demonstrated single-agent anti-tumor activity.
6 MINS LATER
Carmel FischerHOST
Tell us more about that total addressable market and how do investors stand to make some return on their investment here?