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Ian Marber

Ian Marber

Author

Aug 16, 2026

17:26
So for listeners who maybe aren't familiar or aren't clinicians, can you explain how the GLP-1 medications actually work? What is happening physiologically that then leads to weight loss?
17:36
Every time we eat, the body naturally produces GLP, glucagon-like peptide.
17:41
But the GLP that is naturally produced by the body is broken down by something called DPP-4 in about two minutes max.
17:49
We should talk about this later, which we should talk about the supplements that claim to mimic GLP.
17:55
And so it's broken down very, very quickly.
17:58
And so what GLP-1 agonists do is they replicate that, but they bypass DPP-4, which breaks it down.
18:07
So effectively, the medications last for five to seven days.

35 MINS LATER

53:35
The lines blur, don't they? Yeah, see how moral I'm

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