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Gottfried Konecny

German author

May 21, 2026

44:46
And how do you manage grade one versus grade two? And would you reach
44:50
out? Yeah.
44:50
My practice has changed because being involved in the early clinical trials, I must say our approach was a little more nonchalant in the sense that we didn't jump right straight into holding the drug or getting a pulmonologist involved.
45:09
And Ursula's case really shows getting a pulmonologist involved in grade one, making a balanced decision whether steroids are necessary.
45:17
This case, the patient was symptomatic, so I'm surprised they didn't treat her with steroids.
45:22
I think with the recent data, it really requires aggressive mitigation to prevent grade 5 toxicities, and if we do that, hold, get a pulmonologist involved if you have ground glass capacities, do a scan every two months.
45:42
I think we can keep it manageable.

34 MINS LATER

79:19
Gottfried, take us home.

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