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Gary Kaplan

Founder of BetonSports

Jul 21, 2026

7:31
So what are your thoughts with all of that?
7:33
So the first thing you want to think about is that at this point in time, the latest studies say that Alzheimer's is probably about 50% genetically determined, but 50% environmentally determined.
7:45
So that means there are potential interventions that we can do to prevent the onset of the disease if we can diagnose it early enough.
7:52
And indeed, it looks like the markers for Alzheimer's are present somewhere between 10 to 15 years prior to the onset of early cognitive decline and ultimately Alzheimer's.
8:06
So we have a lot of reason, I think, for looking.
8:09
Now, the challenge is, if you're going to look, I have one patient who is P-tau positive in her 50s who does not have any cognitive decline whatsoever.
8:20
She wanted to get this testing done.

20 MINS LATER

28:06
Just even going in for the infusions and stuff, I would think it would be really time-consuming.
MikeHOST
12:15
When it comes to longevity, what are the top hidden stressors that are silently aging people?
12:24
So longevity, okay, basically it's inflammation.
12:28
It's a chronic inflammatory process that's wearing you down.
12:31
So one of the big things is sleep, right? So if you're not getting enough sleep and you're finding that you're waking up, now, let's talk about sleep for a second.
12:44
This is very important, sleep apnea.
12:46
Sleep apnea is when you stop breathing at night.
12:49
That happens to about 5% of the population.

14 MINS LATER

MikeHOST
26:33
My next question is what treatments or therapies at Kaplan Clinic have surprised you the most in terms of reversing stress-related aging?
9:37
Is that all kind of right?
9:39
Yes, and so we have to stop thinking in terms of the symptom, all right, and instead back up and think in terms of the person and look at a much bigger factor.
9:48
So, you know, genetics.
9:50
We are finally getting to the point in genetics of understanding increased risk factors.
9:54
Alzheimer's.
9:55
We can identify people who are on their path to Alzheimer's 10 to 20 years prior to the development of the symptoms of the disease.
10:06
All right? That's a 10 to 20-year window where I can intervene and probably slow down, if not stop, the development of the disease.

22 MINS LATER

32:16
Tell us about the latest science and how it connects to longevity because everybody wants to live longer, but we also want to live well.

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