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Frank Winkler

Frank Winkler

Researcher

Jun 29, 2026

11:32
Mm
11:32
... uh, the, the mean survival, uh, uh, depending on the subgroup, is between 12 and tw- for 24 months.
11:38
So that shows you it's really, um, it's a challenge.
11:41
And so, um, my, our and my, um, uh, my aim was to really understand this disease in a different way and, and, and using a lot of neuroscience technology.
11:53
So, um, chronic cranial window, uh, combined with intravital two-photon microscopy where you can nicely study how- The cancer really progresses in the brain and then combining this with optogenetic methods and all kind of other reporter calcium imaging, et cetera, et cetera.
12:09
So all, all, um, methods really, um, lead from neuroscience.
12:15
And we really discovered that these cancers are much more neuronal themselves, um, by hijacking important neurodevelopmental factors to extend neurite-like extensions or like immature neurons, these early processes.

10 MINS LATER

22:50
Mm

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