Let's start with the, the absolutes.

Yeah.

E- Excellent question.

So when we talk about psychedelics and clinical safety around them, we must understand or distinguish between the psychiatric or psychological risk, uh, and the, uh, physiological risks, the, the, the tangible, physical ones.

Uh, they are both extremely important.

So on the psychiatric risk, uh, uh, profile, there's bipolar Type 1 disorder, there's, uh, uh, psychotic disorders of any kind, and we can do a, a, a small parenthesis here because some substances, uh, that, uh, are problematic for patients can result in psychotic episodes, particularly stimulants.

If you think about, uh, uh, uh, days o- of doing meth, days of doing cocaine or crack, uh, can result in a psychotic episode.

Sure