So Fabien, I have a question for you regarding the current indications for treatment of patients with severe

tricuspid regurgitation.

Thank you very much, Julien, for having me.

I'm very happy to be with you and answer this question.

So obviously, one part of the answer are the guidelines, and the guidelines say that we need to treat this patient.

There is a two-way recommendation now, but the conditions are quite clear.

So they need to be symptomatic, to have some symptoms that are related to triglyceridic agitation, and they need to have severe triglyceridic agitation.

And Fabien, what are nowadays the evidence we have regarding the management of those patients? Why are we going to treat those patients and who are the patients that may benefit from those interventions?