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Ellen Binder
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Oct 15, 2026
Can We Prevent Cognitive Decline in Aging? Multi-Domain Trials with Laura Baker and Ellen Binder
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6:00Ellen BinderGUEST
... with a simple solution, and I think I'll pass the baton at that I was only, I was gonna say that we, we have learned like from fall interventions that multi-component interventions have been more effective because they're able to target more risk factors.
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6:18Ellen BinderGUEST
That's kind of the hypothesis for a lot of the, the trials, uh, such as POINTER and FINGER that are trying to address the multiple risk factors for Alzheimer's disease that we know exist.
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6:33Ellen BinderGUEST
I don't, I don't know yet whether we can pinpoint yet, you know, which components are most effective or, you know, or, or...
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6:43Ellen BinderGUEST
But it's appearing that, just as Laura said, having, um, more components at this early stage of this research seems to have-
25 MINS LATER
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31:58Ellen BinderGUEST
So this was, uh, uh, targeting individuals with vascular risk factors, hypertension, hyperlipidemia, who were either had a family history of Alzheimer's disease, uh, or dementia, or, uh, self-reported memory complaints.
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32:18Ellen BinderGUEST
And it was looking at whether more intensive blood pressure management, a la the SPRINT protocol, basically, getting their blood pressure into the below one thirty, plus, uh, a high-intensity statin.