Okay, so I think when most people hear this, you know, they're thinking, "Oh, is this Ozempic?"

No.

So it's, so it's, it's, it's really different.

So if, if we go back and look at what GLP-1 is, so, you know, GLP-1 in your body.

So GLP-1 in your body is a, a small peptide, so that means a small sort of protein molecule, and it's released every time you have food.

So if you eat a meal, the food gets down into your small intestine, GLP-1 is released by a series of cells called L cells.

And in the body, the main role of GLP-1 is really glucose control, so it helps your body to release insulin, and it makes the insulin more active in the body as well.

Right.

What is this clinical research saying about the effectiveness of Amerisate?

Yeah, so we did several scientific research studies in order to validate efficacy.

Essentially, the first thing we did was we really wanted to show that we had these bitter taste systems in the gastrointestinal tract.

So the first stage of the research was to go into hospital and to ask people to volunteer bits of their intestinal tract, so biopsies from along their intestinal tract, to identify where all of these bitter tasting systems were in the gut and to figure out how was best to target them.

We had 28 people take part of that, and we got this very nice map of the gastrointestinal tract, so we knew exactly where to target and really what to use.

We then did a series of in vitro screening assays, so drug discovery essentially or drug discovery type systems where we looked for what would be best at triggering these bitter taste systems within the gastrointestinal tract.

And then once we found a potent activator, in this case it was a hop extract we called Amarisate, we ran a series of acute clinical trials to really show that it could work in people.

And so, Dr. Walker, where do you see Calicurb fitting into the future of health, especially as this demand for non-pharmaceutical options are growing? Are there any new applications or research directions that you're excited about for Calicurb?