So would you say small absorption differences matter a whole bunch here? Yeah.

They can.

So for an NTI, I definitely would take even more caution and avoid switching those if possible.

Once a patient has been stabilized on a narrow therapeutic index drug, we don't like to change those unless we have to.

But a lot of times, especially these days, that's not in the pharmacist's hands.

The supplier that... their health system, their pharmacy, their buying group, their chain uses, sometimes is going to change that generic product and the pharmacist does not always have as much ability to say, no, no, no, I don't want to change from the blue to the white pill, even though I, as the pharmacist, know they're the same, but especially with narrow therapeutic index drugs.

So with those, there's an extra layer of caution and diligence that goes into talking with the patient, listening to the patient.

Any other takeaway messages you can think that pharmacy staff should think about when it comes to, you know, switching meds or generics?