So if we were able to zoom up into the neuroimmune system, and I hope people are gracious to you, Derek, because obviously it's complex and it's evolving, but what are some things that are going on in that area? Yeah.

Yeah, so I suppose first and foremost, you know, none of the recent work suggests that what's happening in the periphery or in the peripheral nervous system is not important.

And I think that's sometimes forgotten.

You know, in recent years, we hear a lot about central sensitization and nociclastic pain and all of these other descriptors.

And, you know, they are relevant, of course, but that doesn't mean that, you know, that there isn't some ongoing peripheral nociception problem.

What might be causing that, again, is a different question.

But we shouldn't just see pain as being this central nervous system phenomenon.

So how does that, and I know patients don't necessarily need to know how it affects downstream, but like if we talk about sleep, for instance, how does that influence sleep? I guess, these neuroimmune things that are going on.