David, a little bit about how you got to where you are today.

Sure.

First, thank you so much for the opportunity to talk about our work today.

Excited to be here.

So actually, my journey started in Cleveland.

I was born in Cleveland.

From a very early age, I knew I wanted to discover new therapies and work on therapeutic development.

Take us through what is a CAR T-cell, how we make them, and then what is it that you've done to try to speed up this process so we can treat patients in a more timely manner? So, David, why don't you start?