
Danielle Kepics
Board-certified physician assistant and founder of Empowered Medicine in St. George, Utah, specializing in perimenopause, hormone replacement therapy, and women's metabolic health; host of the Strong + Unfiltered podcast.
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Aug 25, 2026
659. GLP-1s Can’t Do It All: The No-BS Truth About Midlife Fat Loss with Danielle Kepics
11:09
11:20

Danielle KepicsGUEST
And then this was, I remember this clear as day, I tell this story a lot, Easter weekend 2022, I went and got certified as a fertility educator.

Danielle KepicsGUEST
For people who don't know, that's like helping prevent pregnancy, achieving pregnancy, cycle health, yada, yada.
5 MINS LATER
53. HRT Myths, Metabolism, and Midlife Health with Danielle Kepics (The Hormone Disconnect Series Episode 4)
10:19
10:29
10:40
10:06
So what was it about that study, I'm guessing you know because you're so deep into the HRT, what was it about that study that was actually debunked, and like, why are we still operating from the old information?

Danielle KepicsGUEST
On a high level, because I don't have the study in front of me or notes about it, what they found was that the problems were with the synthetic hormone replacement, so the equine estrogens.

Danielle KepicsGUEST
I went to a conference and the, the pharmacist was so funny, and she kept calling it, like, the horsey estrogens, and I was like, "Yeah," because you know what synthetic estrogens are fucking made from? Horse pee, you guys.

Danielle KepicsGUEST
That's why you need to get the bioidentical stuff, and you don't need to be at a compounding pharmacy for that.
14:39
So the one thing that you kinda hinted to I think is great to talk about is what about the birth control? So in this series previously, Nicole Jardim was on to talk about birth control, so now we can tie the two together here, and can you clarify what the actual difference is between synthetic hormones and birth control, how birth control is not actually HRT, and what HRT actually is? What are the impacts that's gonna have on a woman's health?
