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Crane Holmes

Crane Holmes

Dr. Crane Holmes, ND, FABNG, is a licensed naturopathic physician in Portland, Oregon specializing in SIBO, digestive health, and Lyme disease at Portland SIBO Specialty.

Jun 16, 2026

18:29
the patients starting to feel better? Are they?
18:31
Yeah, I would say it's a good question.
18:33
My biggest clue into like, I think most treatments, right? I'm sure we can see this in like SIBO patients as well.
18:39
I think the biggest clue that I see is that certain things might get better and certain things might get worse.
18:45
And that is like that I know I'm on the right path.
18:47
like all of a sudden they're having like drenching night sweats right maybe their sleep is terrible but they have tons of energy throughout the day and they're and their stamina is a lot better and they're less they're less depressed and whatever or they are to your point like maybe they're having a ton of diarrhea and you're like is this a this is an antibiotic side effect or is this a herx they're having a ton of diarrhea but like their bloating is completely gone they're able to tolerate more foods like you
21:13
And then biofilms, where do biofilm treatment fit in with the trajectory of treatment?
21:19
Yeah.

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