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Craig Chepke

Jul 14, 2026

13:44
Okay.
13:44
Gabapentin.
13:45
So the molecule gabapentin structurally s- it does look similar to the neurotransmitter GABA, but it actually does not have binding affinity to the, to the GABA receptors.
13:56
It, it works on, it is called a alpha-2-delta ligand, it, which is, uh, working on calcium channels.
14:01
Uh, so very different mechanism, but it does ha- have, uh, for many people, a, a potentially positive benefit for anxiety.
14:09
So this is, um, in- inter- intimately related, uh, tardive dys- or respiratory dyskinesia and anxiety.
14:16
'Cause as I mentioned, imagine you're, uh, uh, well, as Amy talked about, y- you're trying to breathe, and you just, you feel like you're, you can't.

12 MINS LATER

26:32
Can you kind of speak to what your own, um, feelings about whether respiratory dyskinesia is at all well, at, at all known in the community, whether it's psychiatrists, neurologists, or other practitioners? Um, do you feel like it's pretty much unknown, or what, what are your feelings about it?

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