
Chloe West
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Oct 5, 2026
What Psychedelics Actually Do in the Brain, Explained by a Neuroscientist
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Brad HookHOST
Perhaps before we dive deeper into the neuroscience, you could share how New Zealand has been part of your story.

Chloe WestGUEST
So New Zealand really was the beginning of my psychedelic neuroscience journey, which is kind of wild to say.

Chloe WestGUEST
But when I was about ten years old, my family moved to, um, Kawakawa, which is a tiny little town, um, in the North Island.

Chloe WestGUEST
And my dad was a doctor at a hospital in Kawakawa, and we had moved there from our very small town in Georgia, the Bible Belt here in the US.

Chloe WestGUEST
And when I moved there, it was the first time that I was introduced to a lot of topics.
Psychedelic Neuroscientist: Your Brain Is Guessing At Reality | Dr. Chloe West - Ep. 314
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Jade TetaHOST
So give us a little bit about your story and what got you into psychedelics and this work.

Chloe WestGUEST
And I really, from a very young age, was asking pretty deep questions, pretty hard questions about the whole thing.
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What A Neuroscientist Believes About Ayahuasca
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7:34TonyHOST
Like, where would somebody put their piece to start?

Chloe WestGUEST
I would say if you can, therapy, a therapist that is familiar with psychedelics and can help with preparation and integration afterwards.

Chloe WestGUEST
Um, I think a lot of cities around the US have, uh, really great psychedelic communities where people can kind of come together and talk about their experiences.

Chloe WestGUEST
Obviously, after psychedelics, sometimes people wanna make huge changes in their lives, and a lot of times those can be good.
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8:59BrentHOST
And like, what were some of their stories?
A Scientist Explains Why Psychedelics Can Feel More Real Than Reality
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30:33BrentHOST
What were some of their stories?

Chloe WestGUEST
I've talked to people from, you know, 25 to 70. who have experienced religious trauma growing up in evangelical fundamentalist Christianity.

Chloe WestGUEST
And a lot of times, all of these different people have held really harmful beliefs, beliefs about God, kind of like we've talked about already, but also beliefs about the self.
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39:23TonyHOST
okay
How Psychedelics Modify Your Consciousness & Deeper Beliefs | Dr. Chloe West
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17:33Ste LaneHOST
I- I've saw you write about this on your Substack, like the, the main function of the brain or of consciousness, whatever you wanna call it, is primarily a pattern recognition machine, no?

Chloe WestGUEST
So our brains evolved not so that we perceive the world in the most accurate way, but so that we perceive the world in the way that's going to be best for our survival.

Chloe WestGUEST
And so what that means in our normal everyday waking consciousness is filtering a lot out.
20 MINS LATER