And what is the etiology of tics and Tourette's?

That...

Yeah, that's a complex question.

So there was, um, an interesting article, and I'm forgetting, uh, pardon me, I'm forgetting who wrote it, but there was an article that looked at, um, [lip smack] a fellowship-trained pediatric movement specialist and asked them, I forget the number of how many they, they interviewed for this, but asked them if they felt like they could confidently report the pathophysiology behind tics, and only about 25% [laughs] felt like they could.

So I think that's probably to say that the etiology is probably polygenic and, um, not fully well-known.

We know that, um, part of it comes from the, um, cortical, striatal, thalamic, uh, cortical network, um, in the brain, which is just basically a fancy word for the part of the brain that controls kind of the stops, basically the gas and the brakes of movements, how much, um, a movement is initiated and how much movement is suppressed.

There's probably also a dopamine pathway.

... about tics and Tourette's?