And then the other concern is what happens when they quit, right? Are they gaining weight back? But you guys know more about this than I do.

Yeah, these are two big areas, Dan.

The muscle loss concept is very much debated.

First of all, when you lose any kind of weight by any means, you're right, bariatric surgery, drugs, diet and exercise, you don't lose just fat, right? Because if you have obesity, there's extra muscle to hold everything together.

And The Krebs cycle metabolism, you need amino acids to burn energy.

So you can't just lose fat.

There is always a certain percent that is muscle.

What do you feel we are not talking about enough? Or what are things that we really should be focusing on as an area of further research?