
Cameron Carlisle
Cameron Carlisle, MD — Family Medicine resident at Clinica Sierra Vista, Bakersfield, CA; Ross University School of Medicine graduate, Class of 2025
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Jun 12, 2026
Episode 226: Optimizing Sleep
15:04
15:12
15:32
18:44
K
14:56KimGUEST
And, uh, creatine also helps, uh, buffer that by increasing phosphocreatine stores, which allows for faster ATP regeneration.

Cameron CarlisleGUEST
And there's actually studies that show improvements in reaction time, uh, working memory, and, uh, cognitive, uh, performance in sleep-deprived individuals.

Cameron CarlisleGUEST
So a recent 2024 study, uh, revealed that one dose of creatine, 0.35 grams per kilogram, can actually help your brain, uh, perform better after a poor night's sleep, likely by supporting energy production when the brain is depleted.

Cameron CarlisleGUEST
So that's, uh, dividing into four doses of five grams for about five to seven days, and then there's the maintenance dose, which is three to five grams per day, uh, there after the loading phase, so.
K
18:30KimGUEST
So melatonin is actually best for circadian rhythm issues like jet lag or shift work, not for falling asleep or s- uh, sleep, uh, lat- latency.

Cameron CarlisleGUEST
So the dose can be between 0.5 to 3 milligrams, uh, taken 30 to 60 minutes prior to bed.