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Brice Gaudillière

Brice Gaudillière

Professor of Anesthesiology at Stanford University studying systems immunology and precision medicine, with research focus on pregnancy complications and preterm birth prevention.

Jun 24, 2026

16:04
Explain to me what, what does it actually tell you about the behavior of that cell under the influence of a particular medication?
16:11
Yeah.
16:11
So actually, and that's, that's a key, key aspect of the algorithm.
16:15
It tells you both, okay? The-- I told you about the training, right? Then the second part, once the algorithm is trained, is that the, the, this digital twin representation will tell you exactly how a drug is going to modify every cell, uh, that's present in, in, in, in a, a pregnant, a woman during pregnancy, okay? And what is-- how are, you know, the CD4 T cell are going to react when you, when you expose them to aspirin or a combination.
16:46
You know, how a monocyte is going to re-- what pathway is gonna be, uh, different, signaling pathway.
16:51
Uh, and so that's really getting to, you know, single cell level understanding of how these drugs are modifying the entire immune system.
17:00
And by the way, just as a, as a, as a side note, it's amazing how the drugs that we've been screening, you know, they're all developed for a different purpose, and they usually haven't been tested, uh, in such a comprehensive way for their role on the immune system.

7 MINS LATER

23:55
this combination is?

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