
Brice Gaudillière
Professor of Anesthesiology at Stanford University studying systems immunology and precision medicine, with research focus on pregnancy complications and preterm birth prevention.
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OCT 5
Jun 24, 2026
Dr. Brice Gaudillière on the Potential of Aspirin + Lansoprazole to Stop Preterm Birth: A New Clinical Trial
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16:04Olesya PlekheHOST
Explain to me what, what does it actually tell you about the behavior of that cell under the influence of a particular medication?

Brice GaudillièreGUEST
It tells you both, okay? The-- I told you about the training, right? Then the second part, once the algorithm is trained, is that the, the, this digital twin representation will tell you exactly how a drug is going to modify every cell, uh, that's present in, in, in, in a, a pregnant, a woman during pregnancy, okay? And what is-- how are, you know, the CD4 T cell are going to react when you, when you expose them to aspirin or a combination.

Brice GaudillièreGUEST
You know, how a monocyte is going to re-- what pathway is gonna be, uh, different, signaling pathway.

Brice GaudillièreGUEST
Uh, and so that's really getting to, you know, single cell level understanding of how these drugs are modifying the entire immune system.

Brice GaudillièreGUEST
And by the way, just as a, as a, as a side note, it's amazing how the drugs that we've been screening, you know, they're all developed for a different purpose, and they usually haven't been tested, uh, in such a comprehensive way for their role on the immune system.
7 MINS LATER