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Brian Lee

Brian Lee

American retired professional wrestler

May 11, 2026

5:05
... it's not like that, but
5:06
... you know something? I, I, I'll, I ...
5:08
Now that I think about it, in the trailer stuff, a long time ago I was getting a lot of...
5:14
I'm still doing well in trailers, but it, I was getting a lot of campaigns and just getting them.
5:20
Because I had this middle voice that nobody...
5:22
And, and you still had to have a studio, and you had to be professional, and it was all the big guys still doing it, like the Ashtons and the Tony Rogers and-

12 MINS LATER

17:48
Then maybe they recommend you to someone else.
17:50
I think that there is, there is a, there's a, there's a kid that I met in the late '90s, so what? 27 years ago.
16:36
Talk a little bit about this study and how it was conducted and what you ended up finding.
16:42
Uh, yeah, so what my team and I did was we looked at 2.5 million pregnancies, uh, the moms and their children followed up to 20- 20 years or so in Sweden, um, and what we found was, uh, on the surface, a statistical association for a slightly increased risk of acetaminophen used during pregnancy and autism and ADHD, but that's kind of an apples to oranges comparison because the moms who take acetaminophen are very different in many ways from the moms who don't.
17:12
So when you account for the confounding factors, uh, that might explain a statistical association, that association disappears.
17:21
So what we did was a sibling analysis, looking for, uh, siblings where one sibling was exposed and the other sibling was unexposed, and so because the mom's, uh, genetics are being controlled for, uh, this association went away entirely.
17:38
That was pu- uh, that pointed to us that the association was not causation.
17:44
In other words, this was not a causal effect, but most likely due to confounding factors.
18:04
You did a little bit, but maybe get a little more specific.
18:07
Yeah, so basically, the example I use with my students is that eating ice cream is associated with drowning, um, but that's not a causal association, and the real reason behind that association is becau- because hot weather increases your ice cream consumption, and it- it increases your likelihood of going swimming, hence risk of drowning.
21:36
Like, why should I trust your study more than this meta-analysis?
21:41
So one of the fun things with a meta-analysis is that it's a garbage in, garbage out kind of a thing.
21:49
You can feed it garbage, but your meta-analysis is not going to turn this garbage into something beautiful.
21:58
You can repeat the wrong thing many times in completely different samples and get the same wrong results in every single sample.
25:25
And for Brian's part, he really doesn't think the science supports the idea that taking a little Tylenol when you're pregnant makes the kids later become autistic or have ADHD.
25:34
Like, taking off my epidemiologist hat and just, you know, as a person hat, like, blame i- is damaging, it's harmful, like, and it doesn't exactly help.
25:44
People might be blaming themselves for, like, that one random Tylenol they took when, you know, they were pregnant 10 years ago, and, you know, if, if we can help, um, you know, take away some of that guilt that's there, I, I think that's, that's nice because th- people shouldn't be feeling guilty about these things, uh, in the past.

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