Skip to main content
Angela Hirbe

Angela Hirbe

Angela Hirbe, MD, PhD is Associate Professor of Medicine and Pediatrics at Washington University School of Medicine, Director of the Adult Neurofibromatosis Clinical Program and Sarcoma Program.

May 29, 2026

1:36
helping pediatric patients transition to adult care.
1:39
So I think pretty good spread.
1:40
I think all of these are challenges that various providers face and all things that, you know, we plan to touch on today.
1:54
So neurofibromatosis type 1 affects about 120,000 Americans and 2 million people worldwide.
2:01
It's a genetic neurocutaneous disorder that predisposes individuals to develop both benign and malignant tumors.
2:08
And it's caused by a mutation in the NF1 gene, which codes for neurofibromin.
2:14
And neurofibromin functions as a tumor suppressor.

28 MINS LATER

30:20
I
1:37
patients transition to adult care.
1:39
So I think pretty good spread.
1:40
I think all of these are challenges that various providers face and all things that we plan to touch on today.
1:54
So neurofibromatosis type 1 affects about 120,000 Americans and 2 million people worldwide.
2:01
It's a genetic neurocutaneous disorder that predisposes individuals to develop both benign and malignant tumors.
2:08
And it's caused by a mutation in the NF1 gene, which codes for neurofibromin.
2:14
And neurofibromin functions as a tumor suppressor, so losing this results in overactivation of various growth signaling pathways.

28 MINS LATER

30:19
That's all I know.
1:37
patients transition to adult care.
1:39
So I think pretty good spread.
1:40
I think all of these are challenges that various providers face and all things that we plan to touch on today.
1:54
So neurofibromatosis type 1 affects about 120,000 Americans and 2 million people worldwide.
2:01
It's a genetic neurocutaneous disorder that predisposes individuals to develop both benign and malignant tumors.
2:08
And it's caused by a mutation in the NF1 gene, which codes for neurofibromin.
2:14
And neurofibromin functions as a tumor suppressor, so losing this results in overactivation of various growth signaling pathways.

28 MINS LATER

30:19
That's all I know.
1:37
patients transition to adult care.
1:39
So I think pretty good spread.
1:40
I think all of these are challenges that various providers face and all things that we plan to touch on today.
1:54
So neurofibromatosis type 1 affects about 120,000 Americans and 2 million people worldwide.
2:01
It's a genetic neurocutaneous disorder that predisposes individuals to develop both benign and malignant tumors.
2:08
And it's caused by a mutation in the NF1 gene, which codes for neurofibromin.
2:14
And neurofibromin functions as a tumor suppressor, so losing this results in overactivation of various growth signaling pathways.

28 MINS LATER

30:19
That's all I know.
1:36
helping pediatric patients transition to adult care.
1:39
So I think pretty good spread.
1:40
I think all of these are challenges that various providers face and all things that, you know, we plan to touch on today.
1:54
So neurofibromatosis type 1 affects about 120,000 Americans and 2 million people worldwide.
2:01
It's a genetic neurocutaneous disorder that predisposes individuals to develop both benign and malignant tumors.
2:08
And it's caused by a mutation in the NF1 gene, which codes for neurofibromin.
2:14
And neurofibromin functions as a tumor suppressor.

28 MINS LATER

30:20
I

We value your privacy

We use cookies to understand how you use our platform and to improve your experience. Click “Accept All” to consent, or “Decline non-essential” to opt out of non-essential cookies. Read our Privacy Policy.