So I think the first question, I think a very simple question for all three of us might be, what does neurofilament light chain represent for you? Julie, perhaps we could start with you.

Yeah, for sure.

So just to give a bit of context, I'm going to be speaking primarily today from my perspective as someone with lived experience, diagnosed when I was 16 years old.

So I've been living with MS now for over 20 years.

Just to give a bit of context to anyone listening, And I think why it's important and why we're all here today and why I was happy to join the call today was essentially because you don't get much access to being able to know what's going on in your body.

Essentially, when you're diagnosed with MS, you're diagnosed with a disease that's very unpredictable.

You're living with a lot of uncertainty.

Julie, how about from your perspective, is the attraction to a blood-based biomarker different to what Ron's mentioning there?