What are the major findings of the paper?

Yes, so stress CMR detected ischemia in 15.5% of the patients and unrecognized myocardial infarction in 11.7%.

During the follow-up, cardiovascular mortality and not further myocardial infarction, meaning MACE, occurred at a higher rate in patients with ischemia on stress CMR, namely in 5.2% per year, while MACE occurred only in 1.4% per year in patients without ischemia.

The highest MACE rate of 9.2% per year was observed in patients with both myocardial ischemia and unrecognized myocardial infarction.

Thus, this study shows that myocardial ischemia during stress CMR in combination with the presence of unrecognized myocardial infarction, so identified by the late gadolinium enhancement, results in a seven-fold increase of MACE compared to patients with normal CMR.

And the presence of ischemia alone is associated with a five-fold increase in MACE.

These are really impressive numbers that underline the prognostic yield of stress CMR.

Can you explain us a little bit what you found?