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Alan Barber
Neurologist
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Jul 14, 2026
Episode 6: The science behind future stroke prevention
20:32

Clare de LoreHOST
Can you give, without compromising any confidentiality obviously, but can you give me an example of somebody whose life went from under the previous, uh, protocols you had to these newer, faster, FAST protocols and treatments, somebody whose life has been restored to what it was, uh, prior to stroke?
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20:58Alan BarberGUEST
We are now treating, um, I think it's up to about twenty-five, uh, sorry, twenty percent of patients, you know, one in five patients with stroke with one of these treatments.
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21:12Alan BarberGUEST
We're now treating about one in ten of our stroke patients with clot retrieval.
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21:17Alan BarberGUEST
Um, and the important thing about that is the ones who get clot retrieval are the ones with the big clots, the ones we can get at.
7 MINS LATER
ASES Podcast - Episode 152 - Anchors in Rotator Cuff Repair
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13:35Brian WatermanHOST
But, but fundamentally, what, what contributes to that? And is this a-- is this a foregone era, or, or is this something we'll continue to experience with contemporary implants?
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13:47Alan BarberGUEST
Historically, we started off with PGA, polyglycolic acid, for little pins and rods in the ankle fixation arena, and it morphed into other aspects.
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13:59Alan BarberGUEST
And twenty-five percent of those had draining sinuses that were basically due to the rapidity with which that absorbs.
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14:07Alan BarberGUEST
So that if you mix PGA, polyglycolic acid, with polylactile lactic acid and you get a copolymer, then that kind of slows things down.
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14:17Alan BarberGUEST
Or you can go all the way to just pure PLLA, polylactile lactic acid, and that'll take you at least five years, uh, to grade and-- degrade.
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14:32Alan BarberGUEST
And the polymer scientists have tried to hit that sweet spot where it doesn't go away so fast that you get a lytic reaction that's symptomatic, but it does eventually go away.
6 MINS LATER
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20:55Peter ChalmersHOST
Like, how would you respond? What are the concerns you have with that movement in that direction?