Aug 5, 2026 · 8 min · 6 segments
Pavel Osmancik and C. Michael Gibson discuss whether catheter ablation is superior to risk factor modification with antiarrythmic drugs for the treatment of AF.
Pavel OsmancikGuest
C. Michael GibsonHostAre you gonna consider doing a program where you combine the lifestyle management with the ablation to see if it offers advantage over ablation as your follow-on study now that we have more powerful ways of treating obesity?

Uh, in the future, uh, it will be o-of course, nice to combine the treatments because our results had shown that, uh, that to wait for signs with only, uh, only with weight reduction and arrhythmias, it's not as good as with catheter ablation.

But maybe if you do catheter ablation and, and, uh, start a weight reduction program for these patients after catheter ablation, it could be superior, of course.

But the question of this study was not to add weight reduction to an- to ablation, but to look if it's alternatives to catheter ablation.

It was a study that was initiated not by, by, by us, but the patient question.

They have heard about the effect of weight reduction, and they asked, uh, "If we weight, lose weight, uh, do we avoid catheter ablation procedure?" And it doesn't look like this.
Are you gonna consider doing a program where you combine the lifestyle management with the ablation to see if it offers advantage over ablation as your follow-on study now that we have more powerful ways of treating obesity?

Uh, in the future, uh, it will be o-of course, nice to combine the treatments because our results had shown that, uh, that to wait for signs with only, uh, only with weight reduction and arrhythmias, it's not as good as with catheter ablation.

But maybe if you do catheter ablation and, and, uh, start a weight reduction program for these patients after catheter ablation, it could be superior, of course.

But the question of this study was not to add weight reduction to an- to ablation, but to look if it's alternatives to catheter ablation.

It was a study that was initiated not by, by, by us, but the patient question.

They have heard about the effect of weight reduction, and they asked, uh, "If we weight, lose weight, uh, do we avoid catheter ablation procedure?" And it doesn't look like this.
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