Health Topics – Johns Hopkins Medicine Podcasts
Jun 19, 2026 · 1 min · 3 segments
CAR-T cells developed from bone marrow donors whose bone marrow had already been used to treat someone’s cancer may be able to rein in cancer recurrence, a new study finds. Johns Hopkins Kimmel Cancer…
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Elizabeth TracyWe looked at folks who had had bone marrow transplants receiving bone marrow from a different donor we call allogeneic, but the cancer had nonetheless relapsed.
So they made the CAR T cells out of the donor bone marrow.
They tailored the manufacture of these to emphasize stem cell and memory cell properties of the T cells.
They did not need to infuse as many of them.
The side effects, they didn't really see much of that at all, and they persisted for a very long time.
We looked at folks who had had bone marrow transplants receiving bone marrow from a different donor we call allogeneic, but the cancer had nonetheless relapsed.
So they made the CAR T cells out of the donor bone marrow.
They tailored the manufacture of these to emphasize stem cell and memory cell properties of the T cells.
They did not need to infuse as many of them.
The side effects, they didn't really see much of that at all, and they persisted for a very long time.
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