Best Science Medicine Podcast - BS without the BS
May 30, 2026 · 28 min · 10 segments
In episode 622, Jamie and James invite Émélie Braschi back again to talk about if we should be using inhalers that combine corticosteroids and beta-agonists as rescue inhalers. We go over the best…
Émélie BraschiGuestJames McCormackHost
Jamie FalkHostNo entities detected.
... onto the podcast to talk about the evidence around, uh, what, what I think the guidelines are now using, uh, or recommending a lot, which is sort of a combination PRN, uh, um, medication.
So it's the l- use- using, uh, budesonide formoterol as a rescue inhaler for, for asthma.
And so what was the clinical question you guys were trying to answer? And, and I think you did this with, uh, Sam, right?

Um, so the question is, was really to look at what's the evidence around this budesonide formoterol used PRN or as needed.
So the, the, the, the th- the thought is, is, is instead of necessarily using maintenance inhaled corticosteroids is to use a product that contains both a reliever, um, which in this case is formoterol, which is a long-acting beta agonist, but also works as a short-acting, uh, beta agonist and, uh, i- in combination with budesonide.
So every time you have symptoms, rather than taking a maintenance dose of inhaled corticosteroids, you just use this single puffer.
... onto the podcast to talk about the evidence around, uh, what, what I think the guidelines are now using, uh, or recommending a lot, which is sort of a combination PRN, uh, um, medication.
So it's the l- use- using, uh, budesonide formoterol as a rescue inhaler for, for asthma.
And so what was the clinical question you guys were trying to answer? And, and I think you did this with, uh, Sam, right?

Um, so the question is, was really to look at what's the evidence around this budesonide formoterol used PRN or as needed.
So the, the, the, the th- the thought is, is, is instead of necessarily using maintenance inhaled corticosteroids is to use a product that contains both a reliever, um, which in this case is formoterol, which is a long-acting beta agonist, but also works as a short-acting, uh, beta agonist and, uh, i- in combination with budesonide.
So every time you have symptoms, rather than taking a maintenance dose of inhaled corticosteroids, you just use this single puffer.
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