At *The Age of Aging*, we often talk about the importance of physical activity and a healthy diet for brain longevity. However, one of the best things you can do to promote brain health as you age may also seem unlikely: hanging out with your friends.
In this episode, we explore the growing body of research linking social isolation and loneliness to cognitive decline and dementia risk. We’ll hear from older adults navigating loneliness, researchers studying its effects on the brain, and members of a unique housing community designed to help older adults stay connected.
Later, Terrence Casey, Jake Johnson, and Executive Producer Dr. Jason Karlawish reflect on what loneliness looks like in clinical practice, why social isolation can complicate dementia diagnosis and care, and what listeners can do to build stronger social connections throughout their lives.
**Inside this episode**
**5:35 – Social Isolation and Brain Health**
Dr. Holly Elser explains why social isolation is considered one of the 14 modifiable dementia risk factors and how social connection may help build cognitive reserve.
**7:43 – The Dementia Risk of Isolation**
Dr. Barbara Sahakian discusses research from the UK Biobank showing that socially isolated adults had a 26% increased risk of developing dementia.
**11:13 – Grief, Purpose, and Feeling Alone**
Frank Saar reflects on life after the death of his wife and the challenge of rebuilding a sense of purpose while coping with loneliness.
**15:24 – A Community Built for Connection**
Residents and staff from Morningside Gardens in New York describe how a Naturally Occurring Retirement Community (NORC) helps older adults stay socially engaged, active, and supported.
**18:13 – The Social Lives of Healthy Agers**
Philadelphia artist Jean Lindsay shares how decades of participation in community arts programs helped him build friendships and maintain a sense of purpose.
**21:40 – “It’s Okay to Ask for Help”**
Doris Kitt explains why loneliness is deeply personal and why older adults should seek support when isolation begins to affect their well-being.
**24:39 – What Loneliness Looks Like in the Clinic**
Jason Karlawish discusses how social isolation often appears early in dementia and why clinicians pay close attention to changes in a person's daily routines and social engagement.
**34:13 – Finding Your Community Before You Need It**
Jake and Jason discuss why building meaningful social connections earlier in life may be one of the most powerful investments people can make in their long-term brain health.
**Resources available on the episode webpage linked below**
- Check out the 2024 Lancet Commission on Dementia Prevention, Intervention, and Care infographic outlining the 14 modifiable risk factors for dementia.
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- More on Barbara Sahakian
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- Read Dr. Sahakian’s book, Brain Boost
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- Learn more about Morningside Gardens Retirement and Health Services
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- Learn more about Naturally Occurring Retirement Communities
- Sign up for a class at Fleisher Art Memorial
- Resources for older adults experiencing loneliness and social isolation
Special thanks to Doris Kitt, Holly Elser, PhD, Barbara Sahakian, PhD, Frank Saar, Dana Minaya, Ron Bruno, Gene Renzi, as well as today's co-hosts, Terrence Casey, Jake Johnson, and Jason Karlawish, MD.
*The Age of Aging* is a Penn Memory Center production hosted by Producer Jake Johnson and Executive Producer Jason Karlawish. Contributors include Morgann Adams, Terrence Casey, Dalia Elsaid, Emily Largent, and Alison Lynn.
*The Age of Aging* is made possible by generous support from the Michael Naidoff Communications Hub Fund, Lena Chow, and the TIAA Institute.
**Doris Kitt’s Poem on loneliness:**
Life is fraught dear friends
That’s just how it is
The challenge is overcoming and
You don’t have to be a wiz
It’s okay to be sad
Just don’t let it linger
There are lots of things to do
To give loneliness the finger.
Remember the good ole days
And how life used to be
When things were really simpler
Now a memory to you and me.
Doing something different
And keeping busy too
Will bring about a change
You never knew you knew
Teach yourself a language
How hard could it be
Or simply go a fishin’
Or read a book beneath a tree.
Take the train to an unknown stop
Get off and have a cup of tea
Trying something new
Will bring a lot of joy to thee
Volunteer with children
Oh what a day you’ll have
And I guarantee that loneliness
Won’t seem so bad
The idea is to keep busy
Within your capable range
It will make you happy
And your mind will feel the change
Ride a bike. Go skating
Just doing something new
Will make your body healthy
I promise you.
The thoughts that make you lonely
Will be a thing of the past
Have faith. Have hope. Be joyful
And life will be a blast.
No matter what phase of life you’re in
Loneliness can be a drag
It will affect your welfare
And keep you in a bag.
Don’t delay in getting help
If that is what you need
You deserve to live a life of peace
So let others intercede.