Jun 30, 2026 · 50 min · 16 segments
Could chronic inflammatory calcium pyrophosphate deposition disease (CPPD) be hiding in plain sight? In this episode, we explore why CPPD may be far more common than previously recognized, how it can…
Janeth YinGuest
John HausmannHost
[upbeat music] Welcome back to another episode of ACR On Air, the official podcast of the American College of Rheumatology.
We rheumatologists know calcium pyrophosphate deposition disease, or CPPD, through one of its classic presentations, pseudogout.
What if many patients we diagnose with refractory inflammatory arthritis, polymyalgia rheumatica, or erosive osteoarthritis actually have chronic inflammatory CPPD driving at least part of their disease? And what if one reason we're missing it is that we're simply not looking in the right places? My guest today is Dr.
She's Associate Director of the Musculoskeletal Ultrasound Program at Massachusetts General Hospital, and one of the leading experts in musculoskeletal ultrasound in rheumatology.
She previously served for a decade as director of the Rheumatology Musculoskeletal Ultrasound Clinic at Tufts, and she's co-author of "The Clinical Atlas of Musculoskeletal Ultrasound in Rheumatology." And she also contributed to the development of the twenty twenty-three ACR-EULAR classification criteria for CPPD.
In her clinical practice, Dr. Yin has become increasingly interested in the many faces of CPPD, from patients who appear to have seronegative rheumatoid arthritis or polymyalgia rheumatica, to those with unexplained joint damage, tendon rupture, or chronic synovitis.
Her work suggests that CPPD may be far more common and far more consequential than many of us realize.
In this episode, we discuss why chronic inflammatory CPPD is often overlooked, how it can mimic other rheumatic diseases, the role of musculoskeletal ultrasound in diagnosis and management, the structural damage associated with the disease, and where the field may be headed as we search for more effective treatments.
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[upbeat music] Welcome back to another episode of ACR On Air, the official podcast of the American College of Rheumatology.
We rheumatologists know calcium pyrophosphate deposition disease, or CPPD, through one of its classic presentations, pseudogout.
What if many patients we diagnose with refractory inflammatory arthritis, polymyalgia rheumatica, or erosive osteoarthritis actually have chronic inflammatory CPPD driving at least part of their disease? And what if one reason we're missing it is that we're simply not looking in the right places? My guest today is Dr.
She's Associate Director of the Musculoskeletal Ultrasound Program at Massachusetts General Hospital, and one of the leading experts in musculoskeletal ultrasound in rheumatology.
She previously served for a decade as director of the Rheumatology Musculoskeletal Ultrasound Clinic at Tufts, and she's co-author of "The Clinical Atlas of Musculoskeletal Ultrasound in Rheumatology." And she also contributed to the development of the twenty twenty-three ACR-EULAR classification criteria for CPPD.
In her clinical practice, Dr. Yin has become increasingly interested in the many faces of CPPD, from patients who appear to have seronegative rheumatoid arthritis or polymyalgia rheumatica, to those with unexplained joint damage, tendon rupture, or chronic synovitis.
Her work suggests that CPPD may be far more common and far more consequential than many of us realize.
In this episode, we discuss why chronic inflammatory CPPD is often overlooked, how it can mimic other rheumatic diseases, the role of musculoskeletal ultrasound in diagnosis and management, the structural damage associated with the disease, and where the field may be headed as we search for more effective treatments.