Vitamin B6
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Search complete. 340 mentions across 115 episodes found for "Vitamin B6".
Nov 7, 2026
Jin W. SungHOST
Today we're going to talk about B vitamins.
Jin W. SungHOST
In particular, vitamin B6.
Jin W. SungHOST
So let's go into this.
Jin W. SungHOST
Vitamin B6, the forgotten B vitamins.
Jin W. SungHOST
Right.
Jin W. SungHOST
Oftentimes people are talking about, oh, I'm taking B12 or I'm taking folate.
Carrie JonesHOST
So antioxidants.
Carrie JonesHOST
And then lastly, vitamin B6.
Carrie JonesHOST
Vitamin B6 is also indirectly helpful with having all of this work.
Carrie JonesHOST
So if you're not eating a lot of these foods, if you don't absorb a lot of these foods, you struggle with IBS or you have H. pylori in your stomach, you have celiac disease, you have inflammatory bowel disease.
Carrie JonesHOST
Like you just have a lot of things where you're like, oh, I know I don't absorb that well.
Justin MarchegianiHOST
And so if we bypass that enzyme by just giving five HTP, which is one step down that enzymatic chain, we actually can get higher levels of serotonin.
Justin MarchegianiHOST
So typically if we see anyone that has mood issues, we have mood issues, we have sleep issues, right? We're gonna be using five HTP with B6, because B6 is that rate limiting cofactor that helps convert it.
Justin MarchegianiHOST
If you're just doing tryptophan, you tend to have a rate limiting conversion with the hydroxylase enzyme.
Justin MarchegianiHOST
And so then we give the 5-HTP, which then bypasses that governor enzyme, if you will.
Justin MarchegianiHOST
And then we also give the corresponding B6 to bump it up so we can have that optimal conversion.
Justin MarchegianiHOST
All right.
Justin MarchegianiHOST
So if we go back here, benefits of collagen are going to be we have the hydroxyproline, proline, and glycine.
Brittany VincentHOST
If you aren't deficient, but you're wanting to optimize your health, a B-complex or a multivitamin, I think can be a great idea for most individuals.
Brittany VincentHOST
A B complex typically contains a combination of various B vitamins, including B1, B2, B3, B5, B6, folate, biotin, and B12.
Brittany VincentHOST
And then with a multivitamin, you're getting B vitamins, some other vitamins, and then some multivitamins
Brittany VincentHOST
also contain minerals.
Christina EnzmannGUEST
There are some herbal supplements, VTECs.
Christina EnzmannGUEST
There are some vitamins that are helpful, like B6, magnesium.
Christina EnzmannGUEST
All of these things help with the hormone receptors.
Christina EnzmannGUEST
So PMDD, we used to try to treat similarly from the more holistic standpoint.
Maria RisingGUEST
So we started putting additives in.
Maria RisingGUEST
And there has been just like tons and tons of questioning whether additives, B12, glycine, B6, B3, lots of Bs, whatever that is, is actually clinically significant and causing it to not be essentially a copy.
Maria RisingGUEST
Because if additives don't make it different, then we are in patent infringement zone.
Maria RisingGUEST
And that can be a big bad place for telehealth and the compounders.
Bryan ArdisHOST
Now I already mentioned earlier in this show that there's two B vitamins I'm going to introduce you to.
Bryan ArdisHOST
It's vitamin B6 and vitamin B9 called folate or methylfolate.
Bryan ArdisHOST
So these are vitamin B6 breast cancer risk, a 2011 study.
Bryan ArdisHOST
Quote from this study, dietary intake of vitamin B6 was associated with a significantly lower risk of breast cancer among Taiwanese women.
Bryan ArdisHOST
Vitamin B6 plays a critical role in the synthesis of methylene tetrahydrofolate, which is vitamin B9, which is essential for DNA synthesis, repair, and methylation.
Bryan ArdisHOST
How many of you have ever heard of MTHFR, genetic mutation? Did you know vitamin B6 helps with methylation? MTHFR is this inability to methylate, which is why they have to take vitamin B9 and vitamin B12 supplements that are methyl forms.
Bryan ArdisHOST
So those with MTHFR mutation issues, you know I'm talking to you.
Bryan ArdisHOST
Vitamin B6 is already proven to do that, help you methylate.
Bryce WyldeHOST
I'm sure you'd agree.
Bryce WyldeHOST
5-hydroxytryptophan, B6 as a conversion enzyme there is quite often necessary along with B12.
Bryce WyldeHOST
sometimes even magnesium, get the whole thing kind of going.
Bryce WyldeHOST
But to upregulate, increase more serotonin, to be able to manage stress better in this individual, we're definitely going to be giving him some, we're recommending some 5-HTP.
Jared St. ClairHOST
So they're going to be your best form and far more bioavailable and far easier on the body and on the cells as well.
Jared St. ClairHOST
How about B6? This one's very interesting.
Jared St. ClairHOST
Pyridoxine HCL, also very common in, it's pretty much all you see in grocery stores and big box stores, but you'll see it in health food stores too.
Jared St. ClairHOST
And your body has to convert pyridoxine into something called P5P before it can use it.
Jared St. ClairHOST
And that conversion depends on enzymes that need riboflavin, that's B2, and other nutrients to work properly.
Jared St. ClairHOST
There's a bigger issue, though.
Jared St. ClairHOST
Research published in 2017 found that pyridoxine itself in its unconverted form actually blocked the very B6 dependent enzymes it's supposed to support.
Jared St. ClairHOST
So it can actually work against B6 enzymes.
Asa AndrewHOST
And then also, there are certain supplements that can help too.
Asa AndrewHOST
Now, vitamin B5 is always a gold standard for brain chemistry as well as B6.
Asa AndrewHOST
But for acetylcholine, phosphatidylcholine, which is called lecithin, and it's actually found in egg yolks.
Asa AndrewHOST
That's why the eggs were so beneficial and the foods that they listed that can help with acetylcholine levels.
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