What are the features of neurocognitive involvement in children with chronic liver disease or portosystemic shunting? Where to start? That's your business.

I think this is why, together with a group of colleagues within Espigan, we found this acronym SLIPS because we wanted to convey the sense of spectrum.

It really varies from patient to patient.

My hypothesis, or our hypothesis, I should say, is that Since children are affected with their liver disease at different times in their development, the repercussions of liver disease on the brain are going to vary according to the underlying neurodevelopmental, neurocellular processes happening at that given time point.

So to answer your question, the clinical presentation can vary from So I guess there's two points at which you can assess the consequences.

One is at the time of the liver disease, and then the other is later in life.

At the time of liver disease, you might see in the typical little pediatric patient with biliary atresia, you may just see fine motor and gross motor changes that are ascribable to prolonged hospitalization and whatnot.

What are the tricks? Let's do the